Vaccine effectiveness against referral to hospital after SARS-CoV-2 infection in St. Petersburg, Russia, during the Delta variant surge: a test-negative case-control study

Institute for Interdisciplinary Health Research (IIHR)
Publication URL:
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02509-8
Author(s):

Anton Barchuk, Mikhail Cherkashin, Anna Bulina, Natalia Berezina, Tatyana Rakova, Darya Kuplevatskaya, Oksana Stanevich, Dmitriy Skougarevskiy, Artemiy Okhotin

Тип издания:
Журнал
Year of publication:

The results of a randomised trial showed the safety and efficacy of Gam-COVID-Vac against COVID-19. However, compared to other vaccines used across the globe, the real-world data on the effectiveness of Gam-COVID-Vac, especially against the disease caused by the Delta variant of concern, was limited. The authors aimed to assess the effectiveness of vaccination mainly conducted with Gam-COVID-Vac in St. Petersburg, Russia. They estimated the  vaccine effectiveness against referral for hospital admission, COVID-19-related lung injury assessed with LDCT, and decline in oxygen saturation.